The ICMDA Francophone Africa region was created in 2020 to reflect the vibrant work and growth of French speaking groups across the continent. At the 2018 ICMDA World Congress, 10 of the 12 new members welcomed at the event were French speaking groups, with eight of them located in Africa.

In 2023 a further five groups were welcomed into membership of ICMDA.

There is good collaboration and unity among groups with many joint ventures being undertaken and a young and enthusiastic leadership driving the work forward.

325 million people live in the region, with a quarter of them living in DR Congo, however there are just 50 medical schools serving the area, 23 of which are in DRC or Cameroon. With the exception of the smaller islands and Gabon, there are less than two doctors for every 10,000 people and far fewer dentists.

Many countries, particularly in West Africa have been Islamised, practicing an African brand of folk Islam and contain some of the most unreached people groups in the world for the gospel. There remain political and economic challenges for most countries.